Drugs / Ciraparantag
Ciraparantag
also known as
PER977 · CIRAPARANTAG ACETATE · Ciraparantag hexaacetate · ciraprantag · PER-977 ACETATE
Trials 7
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT02205905 | Jul → Aug 2014 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT02206087 | Jun 2014 → Mar 2016 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 1/2 | NCT02206100 | Apr → Aug 2014 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 24 trials · 1 missed | ||||||
| Phase 2 | NCT04593784 | Oct 2021 → Aug 2023 | — | AMAG Pharmaceuticals, Inc. | Terminated | Missed primary Stop: Business |
| Phase 2 | NCT03288454 | Aug 2017 → Aug 2019 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT03172910 | May 2017 → Nov 2019 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT02207257 | Mar 2014 → Sep 2015 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 1 | NCT01826266 Comparator | Jul → Dec 2013 | — | AMAG Pharmaceuticals, Inc. | Completed | No outcome recorded |
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2021-10-04 | Covis Pharma S.à.r.l. | Results New data in the European Heart Journal show ciraparantag reverses the anticoagulant activity of apixaban and rivaroxaban in elderly patients covispharma.com ↗
Ciraparantag produced a rapid and dose-related reversal of anticoagulation induced by apixaban and rivaroxaban compared with placebo in two dose ranging studies in healthy elderly adults (age 50-75 years). |
All press releases naming this drug 2 releases
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Ciraparantag | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03172910 ↗ |
| Known as | CIRAPARANTAG ACETATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL3544919 ↗ |
| Known as | Ciraparantag hexaacetate | ChEMBL registry synonym — accepted as the source's own label CHEMBL3544919 ↗ |
| Known as | ciraprantag | “ciraprantag” NCT02205905 ↗ |
| Known as | PER-977 ACETATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL3544919 ↗ |
| Known as | PER977 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02207257 ↗ |
| Modality | Small molecule | — CHEMBL3544919 ↗ |
| Route | Intravenous | “a single IV dose of PER977” NCT01826266 ↗ |