Drugs / HER2-targeted CAR T cells
last change May 2025 re-read 3 minutes ago

HER2-targeted CAR T cells

Cell therapy

Developed for
bone sarcoma · Ewing sarcoma · Kaposi's sarcoma · malignant germ cell tumor · synovial sarcoma
Investigated by
Essen Biotech

Trials 1

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT07066982 May 2025 → Dec 2027 expected Ewing sarcoma, Kaposi's sarcoma, bone sarcoma, malignant germ cell tumor +1 Essen Biotech Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as HER2-targeted CAR T cells “first an infusion of CD146-targeted CAR T cells, then an infusion of HER2-targeted CAR T cells.” NCT07066982 ↗
Modality Cell therapy “CD146/HER2 Chimeric Antigen Receptor T (CAR T) cells” NCT07066982 ↗
Route Intravenous “patients will receive CD146 HER-2 CAR T cells intravenously (IV)” NCT07066982 ↗