Drugs / HP518
last change Sep 2026 re-read 3 minutes ago

HP518

targets AR

Developed for
prostate carcinoma
Investigated by
Hinova Pharmaceuticals Aus Pty Ltd · Hinova Pharmaceuticals Inc.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05252364 Dec 2021 → Jan 2024 prostate carcinoma Hinova Pharmaceuticals Aus Pty Ltd Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06155084 Dec 2023 → Mar 2026 overdue prostate carcinoma Hinova Pharmaceuticals Inc. Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as HP518 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05252364 ↗
1

NCT06155084 ↗

Route Oral “HP518 once daily orally” PMID 40289067 ↗ Apr 2025
Target AR “HP518 is an oral PROteolysis TArgeting Chimera (PROTAC) protein degrader targeting the wild-type androgen receptor (WT-AR) and mutant AR ligand-binding domain (AR-LBD).” PMID 40289067 ↗ Apr 2025