Drugs / BHQ880
last change Nov 2013 re-read 2 minutes ago

BHQ880

Monoclonal antibody targets DKK1

Developed for
plasma cell myeloma · smoldering plasma cell myeloma
Investigated by
Novartis Pharmaceuticals

Trials 3 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00741377 Jan 2009 → Dec 2011 plasma cell myeloma Novartis Pharmaceuticals Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01337752 Jan 2012 → May 2013 impaired renal function disease, plasma cell myeloma Novartis Pharmaceuticals Completed No outcome recorded
Phase 2 NCT01302886 May 2011 → Nov 2013 smoldering plasma cell myeloma Novartis Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BHQ880 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01302886
2

NCT01337752

NCT00741377

Action Inhibit “Anti-Dickkopf1 (DKK1) Neutralizing Antibody” NCT01302886
Modality Monoclonal antibody Monoclonal Antibody (mAb)” NCT01337752
Route Intravenous “repeated IV doses of BHQ880” NCT00741377
Target DKK1 “Anti-Dickkopf1 (DKK1) Neutralizing Antibody” NCT01302886