Drugs / Ralfinamide
last change Aug 2011 re-read 3 minutes ago

Ralfinamide

Small molecule targets CACNA1B, MAOB via inhibition

Developed for
neuropathy, painful
Investigated by
Newron Pharmaceuticals SPA · CliniRx · Parexel

Trials 2

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00736151 May 2004 → Apr 2007 neuropathy, painful Newron Pharmaceuticals SPA Completed No outcome recorded
Phase 31 trial
Phase 3 NCT01019824 Mar 2009 → May 2010 — Newron Pharmaceuticals SPA Completed No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Ralfinamide ClinicalTrials.gov intervention name — accepted as the source's own label NCT01019824 ↗
1

NCT00736151 ↗

Known as FCE-26742A ChEMBL registry synonym — accepted as the source's own label CHEMBL2107771 ↗
Known as NW1029 ChEMBL registry synonym — accepted as the source's own label CHEMBL2107771 ↗
Known as PNU-0154339E ChEMBL registry synonym — accepted as the source's own label CHEMBL2107771 ↗
Known as Priralfinamida ChEMBL registry synonym — accepted as the source's own label CHEMBL2107771 ↗
Known as Priralfinamide ChEMBL registry synonym — accepted as the source's own label CHEMBL2107771 ↗
Action Inhibit “Voltage-gated N-type calcium channel alpha-1B subunit blocker” CHEMBL2107771 ↗
2

“voltage-dependent, Na+-channel blockade” NCT01019824 ↗

“Monoamine oxidase B inhibitor” CHEMBL2107771 ↗

Modality Small molecule — CHEMBL2107771 ↗
Route Oral “Oral tablets administered at rising doses of 80 - 320 mg/day” NCT00736151 ↗
Target CACNA1B “Voltage-gated N-type calcium channel alpha-1B subunit blocker” CHEMBL2107771 ↗
Target MAOB “Monoamine oxidase B inhibitor” CHEMBL2107771 ↗