Drugs / Intetumumab
last change Jan 2015 re-read 2 minutes ago

Intetumumab

also known as CNTO 95 · CNTO 095

Monoclonal antibody

Developed for
cancer · melanoma · prostate neoplasm
Investigated by
Centocor, Inc. · Genentech, Inc. · Herbert Hurwitz, MD · Janssen-Cilag Farmaceutica, S.R.L.

Trials 3 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00888043 Mar 2009 → Dec 2014 cancer Herbert Hurwitz, MD Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT00246012 May 2005 → Jun 2008 melanoma Centocor, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00537381 May 2007 → Nov 2009 prostate neoplasm Centocor, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Intetumumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT00246012
1

NCT00537381

Known as CNTO 095 ChEMBL registry synonym — accepted as the source's own label CHEMBL1743032
Known as CNTO 95 “An Efficacy and Safety Study of Intetumumab (CNTO 95) in Participants With Metastatic Hormone Refractory Prostate Cancer” NCT00537381
1

NCT00888043

Action Inhibit “CNTO 95 is a fully humanized monoclonal antibody that blocks integrin αvβ3 with high affinity.” NCT00888043
Modality Monoclonal antibody “the Human Monoclonal Antibody to Human α ν Integrins (CNTO 95)” NCT00246012
Route Intravenous “Intetumumab will be administered at the dose of 3 milligram per kilogram (mg/kg) as intravenous infusion” NCT00246012