Drugs / TRC253
last change Nov 2020 re-read 3 minutes ago

TRC253

Small molecule targets AR via inhibition

Developed for
castration-resistant prostate carcinoma · prostate adenocarcinoma
Investigated by
Janssen Pharmaceutica N.V., Belgium · Tracon Pharmaceuticals Inc.

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT02987829 May 2017 → Oct 2019 castration-resistant prostate carcinoma, prostate adenocarcinoma Tracon Pharmaceuticals Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TRC253 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02987829 ↗
Action Inhibit “with inhibitory activity against wild type AR” NCT02987829 ↗
Modality Small molecule “TRC253 is a high-affinity, small molecule antagonist of the androgen receptor (AR)” NCT02987829 ↗
Route Oral “TRC253 is orally active” NCT02987829 ↗
Target AR “antagonist of the androgen receptor (AR)” NCT02987829 ↗