Drugs / Matuzumab
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00113581 | Oct 2002 → May 2006 | esophageal cancer, gastric cancer | Merck KGaA, Darmstadt, Germany | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT00215644 | Aug 2005 → Jul 2008 | esophageal cancer, gastric cancer | Merck KGaA, Darmstadt, Germany | Completed | No outcome recorded |
| Phase 2 | NCT00111839 | May 2005 → Jul 2007 | non-small cell lung carcinoma | EMD Serono | Completed | No outcome recorded |
| Phase 2 | NCT00073541 | Apr 2003 → Mar 2004 | ovarian cancer | EMD Serono | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | matuzumab | “A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies.” PMID 17126894 ↗ Nov 2006 |
| Known as | EMD 72000 | “This open-label, multicenter, randomized, controlled, Phase II study is planned to answer questions about how the drug, matuzumab (EMD 72000), works and is part of an effort...” NCT00111839 ↗3“A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies.” PMID 17126894 ↗ Nov 2006 “EMD 72000 (matuzumab)” NCT00113581 ↗ |
| Action | Inhibit | “EMD 72000 blocks a factor found on the surface of many cancer cells.” NCT00073541 ↗ |
| Modality | Monoclonal antibody | “a humanized anti-EGFR monoclonal antibody” PMID 17126894 ↗ Nov 2006 |
| Route | Intravenous | “Matuzumab will be administered IV until PD or the occurrence of unacceptable toxicity.” NCT00111839 ↗ |
| Target | EGFR | “the epidermal growth factor receptor (EGFR)-targeting monoclonal antibody matuzumab” PMID 20978446 ↗ Dec 2010 |