Drugs / Ulodesine
last change Feb 2013 re-read 2 minutes ago

Ulodesine

Small molecule targets PNP via inhibition

Developed for
gout
Investigated by
BioCryst Pharmaceuticals

Trials 4 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01407874 Sep 2011 → Jul 2012 arthritic joint disease, gout, impaired renal function disease BioCryst Pharmaceuticals Completed No outcome recorded
Phase 2 NCT01265264 Dec 2010 → Jul 2012 arthritic joint disease, gout BioCryst Pharmaceuticals Completed No outcome recorded
Phase 2 NCT01129648 May → Nov 2010 gout BioCryst Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00985127 Sep 2009 → Sep 2010 gout BioCryst Pharmaceuticals Completed No outcome recorded

Evidence & citations 13 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Ulodesine ClinicalTrials.gov intervention name — accepted as the source's own label NCT01407874
1

NCT01265264

Known as BCX-3408 ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Known as BCX-4208 HEMISUCCINATE HYDRATE ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Known as BCX4208 “Ulodesine (BCX4208) 5 mg” NCT01407874
2

NCT01129648

NCT00985127

Known as Dadme-immucillin h ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Known as LR-09 ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Known as R-3421 ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Known as Ulodesina ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Known as ULODESINE SUCCINATE ChEMBL registry synonym — accepted as the source's own label CHEMBL269864
Action Inhibit “Purine nucleoside phosphorylase inhibitor” CHEMBL269864
Modality Small molecule CHEMBL269864
Route Oral Oral dose administered daily for 84 days.” NCT01265264
Target PNP “Purine nucleoside phosphorylase inhibitor” CHEMBL269864