Drugs / Autologous Human Schwann Cells
last change Dec 2025 re-read 3 minutes ago

Autologous Human Schwann Cells

also known as ahSC

Cell therapy

Developed for
paraplegia · peripheral nerve lesion · spinal cord injury · lesion of sciatic nerve · quadriplegia · sciatic neuropathy
Investigated by
W. Dalton Dietrich · The Miami Project to Cure Paralysis

Trials 6

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT03999424 Sep 2019 → Dec 2025 peripheral nerve lesion W. Dalton Dietrich Completed No outcome recorded
Phase 1 NCT02354625 Jan 2015 → Aug 2019 paraplegia, quadriplegia, spinal cord injury W. Dalton Dietrich Completed No outcome recorded
Phase 1 NCT01739023 Nov 2012 → Aug 2016 paraplegia, spinal cord injury W. Dalton Dietrich Completed No outcome recorded
Phase not stated3 trials
— NCT04465929 — peripheral nerve lesion W. Dalton Dietrich No longer available No outcome recorded
— NCT02480777 — lesion of sciatic nerve W. Dalton Dietrich No longer available No outcome recorded
— NCT02510079 — sciatic neuropathy W. Dalton Dietrich No longer available No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Autologous Human Schwann Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04465929 ↗
5

NCT02510079 ↗

NCT02354625 ↗

NCT01739023 ↗

NCT02480777 ↗

NCT03999424 ↗

Known as ahSC “As a part of a Phase I clinical trial to assess the safety of autologous human Schwann cells (ahSC) in persons with chronic spinal cord injury (SCI), participants engaged in a...” PMID 32493977 ↗ Jun 2020
1

“autologous human Schwann cells (ahSC) transplantation” NCT01739023 ↗

Action Restore “For humans with chronic SCI, we hypothesize that axons might show improved function if myelin repair is induced with the implantation of ahSC.” NCT02354625 ↗
Modality Cell therapy “cell-based treatment strategy” NCT01739023 ↗
Route Other “administered via a single injection into the cavity of the spinal cord lesion” NCT01739023 ↗