Drugs / DAZCAPISTAT
last change Jul 2021 re-read 3 minutes ago

DAZCAPISTAT

also known as BLD-2660

Small molecule

Developed for
idiopathic pulmonary fibrosis · COVID-19
Investigated by
Blade Therapeutics

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04001998 Feb → Jun 2021 — Blade Therapeutics Withdrawn No outcome recorded
Phase 1 NCT03559166 Jul 2018 → Oct 2019 — Blade Therapeutics Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04244825 Dec 2019 → Sep 2020 idiopathic pulmonary fibrosis Blade Therapeutics Withdrawn No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT04334460 Comparator May → Nov 2020 COVID-19 Blade Therapeutics Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as DAZCAPISTAT ChEMBL registry synonym — accepted as the source's own label CHEMBL5095225 ↗
Known as BLD-2660 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03559166 ↗
3

NCT04334460 ↗

NCT04001998 ↗

NCT04244825 ↗

Action Inhibit “inhibitor of calpain (CAPN) 1, 2, and 9” NCT04334460 ↗
Modality Small molecule “small molecule inhibitor” NCT04334460 ↗
Route Oral “Single oral dose of BLD-2660 or placebo capsule administered to healthy volunteers” NCT03559166 ↗