Drugs / Acetyl Hexapeptide-8
Acetyl Hexapeptide-8
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00942851 | Jul 2009 → Oct 2010 | focal dystonia | National Institute of Neurological Disorders and Stroke (NINDS) | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT01381484 | Mar → Sep 2009 | — | Mahidol University | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 2 | NCT01750346 Comparator | Nov 2012 → May 2015 | focal dystonia | National Institute of Neurological Disorders and Stroke (NINDS) | Terminated | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | acetyl hexapeptide-8 | “To study the efficacy of cutaneous application of Acetyl Hexapeptide-8 (AH8) in the therapy of blepharospasm.” NCT00942851 ↗ |
| Known as | AH-8 | “Acetyl Hexapeptide-8 (AH-8) is the active ingredient in a number of cosmetic creams used to treat wrinkles, and is marketed under the trade name Argireline(Copyright).” NCT00942851 ↗1“Participants in the 0.05% AH-8 arm received the higher dose of the study drug, Acetyl Hexapeptide 8 (AH-8), which is sold under the brand name, Argireline.” NCT01750346 ↗ |
| Known as | Argireline | “Participants in the 0.05% AH-8 arm received the higher dose of the study drug, Acetyl Hexapeptide 8 (AH-8), which is sold under the brand name, Argireline.” NCT01750346 ↗ |
| Known as | Argireline(Copyright) | “Acetyl Hexapeptide-8 (AH-8) is the active ingredient in a number of cosmetic creams used to treat wrinkles, and is marketed under the trade name Argireline(Copyright).” NCT00942851 ↗ |
| Action | Inhibit | “Argireline has mechanism of action that significantly inhibited neurotransmitter release with a potency similar to that of BoNTA.” NCT01381484 ↗ |
| Modality | Peptide | “These findings demonstrate that Argireline is a anti-wrinkle peptide that emulates the action of currently used BoNTs.” NCT01381484 ↗ |
| Route | Topical | “as a skin cream instead of an injection” NCT00942851 ↗ |