Drugs / Flumatinib

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 23 trials
Phase 2 NCT05433532 May 2022 → Apr 2024 Philadelphia-positive myelogenous leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, mixed phenotype acute leukemia The First Affiliated Hospital of Soochow University Completed No outcome recorded
Phase 2 NCT02511340 Jan 2013 → Aug 2015 chronic myeloid leukemia Jiangsu Hansoh Pharmaceutical Co., Ltd. Unknown No outcome recorded
Phase 2 NCT01503502 Aug 2011 → Jun 2012 chronic myeloid leukemia Jiangsu HengRui Medicine Co., Ltd. Unknown No outcome recorded
Phase 32 trials
Phase 3 NCT04375683 Mar 2020 → Dec 2022 B-cell adult acute lymphocytic leukemia, B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) Zhongda Hospital Unknown No outcome recorded
Phase 3 NCT02204644 Jun 2014 → Jun 2017 chronic myeloid leukemia Jiangsu Hansoh Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 44 trials
Phase 4 NCT05367765 Apr 2022 → Apr 2027 expected chronic myeloid leukemia Jiangsu Hansoh Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 4 NCT05353205 Nov 2021 → Dec 2022 chronic myeloid leukemia Jiangsu Hansoh Pharmaceutical Co., Ltd. Unknown No outcome recorded
Phase 4 NCT05071482 Sep 2021 → Jan 2023 acute leukemia Institute of Hematology & Blood Diseases Hospital, China Terminated No outcome recorded
Phase 4 NCT04677439 Jan 2021 → May 2023 chronic myeloid leukemia Shenzhen Second People's Hospital Unknown No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06530810 Background Jul 2024 → May 2026 overdue leukemia, myeloid, accelerated-phase Jiangsu Hansoh Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 41 trial
Phase 4 NCT04933526 Comparator Jul 2021 → Apr 2023 chronic myeloid leukemia Shenzhen Second People's Hospital Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as Flumatinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT04933526
10

NCT05353205

NCT02204644

NCT01503502

NCT02511340

NCT05071482

NCT04677439

NCT06530810

NCT05433532

NCT04375683

NCT05367765

Action Inhibit “Flumatinib has been shown to be a more potent inhibitor of BCR-ABL1 tyrosine kinase than imatinib.” PMID 32928796 Sep 2020
Modality Small molecule “Flumatinib is the first approved second generation TKI in China and a derivative of imatinib.” NCT04375683
Route Oral “The starting daily oral dose of Flumatinib is 600mg” NCT02511340
Target ABL1 “Flumatinib, a TKI with more potent binding affinity for BCR-ABL1 tyrosine kinase than imatinib” NCT05071482