Drugs / AZD7624
last change Feb 2019 re-read 3 minutes ago

AZD7624

Small molecule targets MAPK14 via inhibition

Developed for
chronic obstructive pulmonary disease · asthma
Investigated by
AstraZeneca

Trials 4

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01937338 Oct 2013 → Apr 2014 — AstraZeneca Completed No outcome recorded
Phase 1 NCT01817855 Sep 2013 → Oct 2014 chronic obstructive pulmonary disease AstraZeneca Completed No outcome recorded
Phase 1 NCT01754844 Jan → Aug 2013 chronic obstructive pulmonary disease AstraZeneca Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT02238483 Oct 2014 → Apr 2016 chronic obstructive pulmonary disease AstraZeneca Completed Missed primary
Comparator or background therapy1 trial
Phase 2 NCT02753764 Comparator Jan 2017 → Feb 2019 asthma National Jewish Health Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as AZD7624 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01817855 ↗
4

NCT01937338 ↗

NCT02238483 ↗

NCT02753764 ↗

NCT01754844 ↗

Action Inhibit “ability of AZD7624 to inhibit p38 MAPK activity” NCT02753764 ↗
1

“MAP kinase p38 alpha inhibitor” CHEMBL9960 ↗

Modality Small molecule — CHEMBL9960 ↗
Route Inhaled “Single dose inhaled IMP via a nebulizer” NCT01754844 ↗
Target MAPK14 “MAP kinase p38 alpha inhibitor” CHEMBL9960 ↗