Drugs / N-acetyl D-mannosamine
last change Dec 2025 re-read 3 minutes ago

N-acetyl D-mannosamine

also known as ManNAc · N-acetylmannosamine

Other / unclassified

Developed for
kidney disorder
Investigated by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02639260 Jul 2016 → Jun 2018 kidney disorder National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as N-acetyl D-mannosamine ClinicalTrials.gov intervention name — accepted as the source's own label NCT02639260 ↗
Known as ManNAc “ManNAc (N-acetyl D-mannosamine) is an uncharged monosaccharide that is the biologic precursor of N-acetyl neuraminic acid (Neu5Ac, sialic acid).” NCT02639260 ↗
Known as N-acetylmannosamine “oral administration of the metabolic SA precursor, N-acetylmannosamine (ManNAc) restored sialylation and reduced proteinuria, suggesting therapeutic potential.” PMID 41630898 ↗ Dec 2025
Action Restore “N-acetylmannosamine (ManNAc) restored sialylation and reduced proteinuria” PMID 41630898 ↗ Dec 2025
Modality Other / unclassified “ManNAc (N-acetyl D-mannosamine) is an uncharged monosaccharide” NCT02639260 ↗
Route Oral “oral ManNAc” NCT02639260 ↗