Drugs / Volinanserin
last change Mar 2009 re-read 9 days ago

Volinanserin

Small molecule targets HTR2A via inhibition

Developed for
sleep disorder, initiating and maintaining sleep · depressive disorder
Investigated by
Sanofi · National Institute of Mental Health (NIMH)

Trials 5

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00070694 Sep 2003 → Oct 2004 depressive disorder National Institute of Mental Health (NIMH) Completed No outcome recorded
Phase 34 trials
Phase 3 NCT00788515 Nov 2008 → Jan 2009 sleep disorder, initiating and maintaining sleep Sanofi Terminated No outcome recorded
Phase 3 NCT00495885 Jun 2007 → Oct 2008 sleep disorder, initiating and maintaining sleep Sanofi Completed No outcome recorded
Phase 3 NCT00464061 Apr 2007 → Mar 2009 sleep disorder, initiating and maintaining sleep Sanofi Terminated No outcome recorded
Phase 3 NCT00464243 Apr 2007 → Jan 2008 sleep disorder, initiating and maintaining sleep Sanofi Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as volinanserin ClinicalTrials.gov intervention name — accepted as the source's own label NCT00495885 ↗
3

NCT00464243 ↗

NCT00464061 ↗

NCT00788515 ↗

Known as M100907 “Drug: Volinanserin (M100907)” NCT00788515 ↗
1

“volinanserin (M100907)” NCT00495885 ↗

Known as MDL100.907 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00070694 ↗
Known as Volinanserina ChEMBL registry synonym — accepted as the source's own label CHEMBL74355 ↗
Known as Volinanserine ChEMBL registry synonym — accepted as the source's own label CHEMBL74355 ↗
Action Inhibit “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL74355 ↗
1

“5-HT2A antagonist” NCT00070694 ↗

Modality Small molecule — CHEMBL74355 ↗
Route Oral “oral administration” NCT00464061 ↗
Target HTR2A “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL74355 ↗