Drugs / Nolasiban
last change Nov 2020 re-read 3 minutes ago

Nolasiban

also known as OBE001 · Erlosiban

Small molecule targets OXTR via inhibition

Developed for
infertility disorder · female infertility
Investigated by
ObsEva SA

Trials 4

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT02326142 Mar 2015 → Oct 2016 — ObsEva SA Terminated No outcome recorded
Phase 2 NCT02310802 Nov 2014 → Nov 2015 female infertility ObsEva SA Completed No outcome recorded
Phase 32 trials
Phase 3 NCT03758885 Jan → Nov 2019 infertility disorder ObsEva SA Completed No outcome recorded
Phase 3 NCT03081208 Mar 2017 → Mar 2018 infertility disorder ObsEva SA Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Nolasiban ClinicalTrials.gov intervention name — accepted as the source's own label NCT03758885 ↗
1

NCT03081208 ↗

Known as Erlosiban ChEMBL registry synonym — accepted as the source's own label CHEMBL1254025 ↗
Known as OBE001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02326142 ↗
1

NCT02310802 ↗

Action Inhibit “the oxytocin receptor antagonist OBE001” NCT02310802 ↗
1

“Oxytocin receptor antagonist” CHEMBL1254025 ↗

Modality Small molecule — CHEMBL1254025 ↗
Route Oral “single oral administration” NCT02310802 ↗
Target OXTR “Oxytocin receptor antagonist” CHEMBL1254025 ↗