Drugs / Axi-cel
last change Dec 2025 re-read 3 minutes ago

Axi-cel

Cell therapy

Developed for
large B-cell lymphoma · diffuse large B-cell lymphoma
Investigated by
Genentech, Inc. · Kite, A Gilead Company · M.D. Anderson Cancer Center

Trials 1

202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT06213311 May 2024 → Jul 2027 expected large B-cell lymphoma M.D. Anderson Cancer Center Recruiting No outcome recorded
Comparator or background therapy2 trials
Phase 1/2 NCT05370547 Background May 2022 → Jun 2024 non-Hodgkin lymphoma Chinese PLA General Hospital Unknown No outcome recorded
Phase 2 NCT05641428 Comparator Oct 2022 → Dec 2025 overdue diffuse large B-cell lymphoma University Medical Center Groningen Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Axi-cel “A single infusion of CAR-transduced autologous T cells administered intravenously at a target dose of 100 × 10\^6 for Relma-cel or 2 × 10\^6/kg for Axi-cel.” NCT05370547 ↗
2

NCT06213311 ↗

NCT05641428 ↗

Modality Cell therapy “CAR-transduced autologous T cells” NCT05370547 ↗
Route Intravenous “CAR-transduced autologous T cells administered intravenously” NCT05370547 ↗