Drugs / HS-10370
last change Apr 2026 re-read 2 minutes ago

HS-10370

Small molecule targets KRAS via inhibition

Developed for
non-small cell lung carcinoma · colorectal cancer · neoplasm
Investigated by
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06963502 May 2025 → Dec 2028 expected colorectal cancer, non-small cell lung carcinoma Jiangsu Hansoh Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06594874 Oct 2024 → Oct 2026 expected non-small cell lung carcinoma Jiangsu Hansoh Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT05367778 Jun 2022 → Apr 2025 overdue neoplasm Jiangsu Hansoh Pharmaceutical Co., Ltd. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as HS-10370 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05367778
2

NCT06594874

NCT06963502

Action Inhibit inhibitor of KRAS G12C” NCT05367778
Modality Small molecule “HS-10370 is an oral, highly selective, small molecular inhibitor of KRAS G12C.” NCT05367778
Route Oral “HS-10370 will be administered orally once daily in a continuous regimen” NCT05367778
Target KRAS “inhibitor of KRAS G12C” NCT05367778