Drugs / UMIKIBART
last change Dec 2021 re-read 2 minutes ago

UMIKIBART

also known as YYB101

Monoclonal antibody targets HGF via inhibition

Developed for
cancer · colorectal cancer
Investigated by
CellabMED · Yooyoung Pharmaceutical Co., Ltd.

Trials 2 · a red edge is where a trial was stopped

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02499224 Jul 2015 → Jul 2018 cancer CellabMED Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT04368507 Aug 2019 → Dec 2021 colorectal cancer CellabMED Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as UMIKIBART ChEMBL registry synonym — accepted as the source's own label CHEMBL6068187
Known as YYB101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04368507
1

NCT02499224

Action Inhibit “Hepatocyte Growth Factor (HGF)-Neutralizing” NCT04368507
Modality Monoclonal antibody “a humanized monoclonal antibody against hepatocyte growth factor (HGF)” PMID 32536979 Jun 2020
Route Intravenous “YYB101 was administered intravenously to refractory cancer patients” PMID 32536979 Jun 2020
Target HGF “a humanized monoclonal antibody against hepatocyte growth factor (HGF)” PMID 32536979 Jun 2020