Drugs / GTx-758
last change Nov 2016 re-read 2 minutes ago

GTx-758

also known as Capesaris

Small molecule targets ESR1 via activation

Developed for
prostate cancer
Investigated by
GTx

Trials 4 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01615120 Aug 2012 → Nov 2016 prostate cancer GTx Completed No outcome recorded
Phase 2 NCT01420861 Sep 2011 → Dec 2012 prostate cancer GTx Terminated No outcome recorded
Phase 2 NCT01393119 Aug 2011 → Dec 2012 prostate cancer GTx Terminated No outcome recorded
Phase 2 NCT01326312 Jun 2011 → Dec 2012 prostate cancer GTx Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as GTx-758 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01393119
3

NCT01326312

NCT01420861

NCT01615120

Known as Capesaris ChEMBL registry synonym — accepted as the source's own label CHEMBL3545017
Action Activate “GTx-758 is a nonsteroidal selective ER agonist” NCT01326312
1

“Estrogen receptor alpha agonist” CHEMBL3545017

Modality Small molecule “3-fluoro-N-( 4-fluorophenyl)-4-hydroxy-N-( 4-hydroxyphenyl) benzamide” NCT01393119
Route Oral “one GTx-758 tablet orally administered daily” NCT01615120
Target ESR1 “Estrogen receptor alpha agonist” CHEMBL3545017