Drugs / Pexacerfont
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT01656577 | Jun 2012 → Sep 2015 | — | National Institute on Drug Abuse (NIDA) | Terminated | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00135421 | Nov 2005 → Oct 2007 | major depressive disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT00399438 | Dec 2006 → Oct 2007 | irritable bowel syndrome | Bristol-Myers Squibb | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT00481325 | Jul 2007 → Mar 2008 | generalized anxiety disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT01227980 Comparator | Oct 2010 → Jul 2014 | alcohol dependence, anxiety disorder | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Pexacerfont | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00135421 ↗ |
| Known as | BMS-562086 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00399438 ↗ |
| Known as | CRF1 ANTAGONIST | ChEMBL registry synonym — accepted as the source's own label CHEMBL482950 ↗ |
| Known as | Dpc-a69448 | ChEMBL registry synonym — accepted as the source's own label CHEMBL482950 ↗ |
| Action | Inhibit | “Corticotropin releasing factor receptor 1 antagonist” CHEMBL482950 ↗1“pexacerfont, a selective CRF-1 receptor antagonist” PMID 20455246 ↗ May 2010 |
| Modality | Small molecule | — CHEMBL482950 ↗ |
| Route | Oral | “Oral” NCT00135421 ↗ |
| Target | CRHR1 | “Corticotropin releasing factor receptor 1 antagonist” CHEMBL482950 ↗ |