Drugs / Carica Papaya Leaf Extract
Carica Papaya Leaf Extract
Trials 4
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT01943136 | Aug 2013 → Jun 2015 | impetigo | Philippine Dermatological Society | Unknown | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT07172100 | Oct → Nov 2025 overdue | dengue disease | Ziauddin Hospital | Enrolling by invitation | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT06121934 | Oct → Dec 2023 | dengue disease | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT05360134 | Jan 2021 → Oct 2022 | thrombocytopenia | Institute of Liver and Biliary Sciences, India | Unknown | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 1/2 | NCT06945679 Comparator | Jun 2024 → Feb 2025 | dengue disease | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Carica papaya leaf extract | “Carica Papaya leaf extract can be used as supportive treatment for thrombocytopenic disorders and dengue hemorrhagic fever which may be an alternative to platelet transfusions.” NCT06945679 ↗4“This will be a placebo-controlled, multicenter-randomized prospective study of CPLE (Carica papaya leaf extract) tabs in dengue patients (WHO-Group A, B).” NCT06121934 ↗ “Drug: Carica Papaya Leaf Extract” NCT06121934 ↗ |
| Known as | Caripill | “To correlate the change in platelet counts and subsequent response with or without CPLE (Caripill) to the phase of dengue (febrile/critical/ convalescent).” NCT06121934 ↗ |
| Known as | CPLE | “The goal of this clinical trial is to evaluate whether Carica papaya leaf extract (CPLE) can improve platelet counts in children aged 2 to 12 years diagnosed with dengue fever...” NCT07172100 ↗2“This will be a placebo-controlled, multicenter-randomized prospective study of CPLE (Carica papaya leaf extract) tabs in dengue patients (WHO-Group A, B).” NCT06121934 ↗ |
| Known as | Papaya (Carica Papaya) Leaf Extract | “Topical Papaya (Carica Papaya) Leaf Extract 1% Ointment” NCT01943136 ↗ |
| Known as | Papaya leaf extract | “topical papaya leaf extract ointment compared to mupirocin ointment” NCT01943136 ↗ |
| Action | Inhibit | “A recent study showed that flavonoids, present in Carica papaya inhibits NS2B-NS3 protease which can prevent the DEN-2 Virus assembly.” NCT06945679 ↗ |
| Modality | Traditional medicine (herbal / TCM) | “Many studies on herbal medicine have suggested that Carica Papaya has a potential role in increasing platelet count by increasing megakaryopoiesis, decreasing platelet...” NCT06945679 ↗ |
| Route | Topical | “one-week twice-daily application of topical papaya leaf extract ointment compared to mupirocin ointment” NCT01943136 ↗ |