Drugs / NEVADISTINEL
last change Dec 2022 re-read 3 minutes ago

NEVADISTINEL

also known as NYX-3054 · NYX-458

Small molecule

Developed for
cognitive impairment with or without cerebellar ataxia · Lewy body dementia · Parkinson disease
Investigated by
Aptinyx · CogState Ltd. · Worldwide Clinical Trials

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04148391 Nov 2019 → Dec 2022 overdue Lewy body dementia, Parkinson disease, cognitive impairment with or without cerebellar ataxia Aptinyx Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as NEVADISTINEL ChEMBL registry synonym — accepted as the source's own label CHEMBL5314586 ↗
Known as NYX-3054 ChEMBL registry synonym — accepted as the source's own label CHEMBL5314586 ↗
Known as NYX-458 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04148391 ↗
Modality Small molecule “NYX-458 is a small molecule that modulates the N-methyl-D-aspartate receptor (NMDAR).” NCT04148391 ↗
Route Oral “Single oral dose taken daily for 12 weeks.” NCT04148391 ↗