Drugs / Gatipotuzumab
last change Dec 2021 re-read 2 minutes ago

Gatipotuzumab

also known as PankoMab-GEX

Monoclonal antibody targets MUC1

Developed for
cancer · fallopian tube cancer · malignant epithelial tumor of ovary · primary peritoneal carcinoma
Investigated by
Glycotope GmbH

Trials 3 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03360734 Nov 2017 → May 2020 cancer Glycotope GmbH Completed No outcome recorded
Phase 1 NCT01222624 Nov 2009 → Dec 2012 cancer Glycotope GmbH Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01899599 Sep 2013 → Apr 2017 fallopian tube cancer, malignant epithelial tumor of ovary, primary peritoneal carcinoma Glycotope GmbH Completed No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2018-07-30 Daiichi Sankyo Daiichi Sankyo Enters Worldwide Licensing Agreement with Glycotope for Gatipotuzumab Antibody Drug Conjugate daiichisankyo.com

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Gatipotuzumab Gatipotuzumab is a humanized monoclonal antibody recognizing the carbohydrate-induced epitope of the tumor-associated mucin-1 (TA-MUC1).” PMID 34920291 Dec 2021
1

NCT03360734

Known as PankoMab-GEX “Gatipotuzumab (PankoMab-GEX®) is a novel glyco-engineered humanized monoclonal antibody” NCT03360734
1

NCT01222624

Modality Monoclonal antibody “A phase I study of PankoMab-GEX, a humanised glyco-optimised monoclonal antibody to a novel tumour-specific MUC1 glycopeptide epitope in patients with advanced carcinomas.” PMID 27285281 Jun 2016
Route Intravenous “received PankoMab-GEX intravenously every 3 (Q3W), 2 (Q2W), or 1 (QW) week” PMID 27285281 Jun 2016
Target MUC1 “high affinity to a novel tumour-specific glycopeptide epitope of MUC1 (TA-MUC1)” PMID 27285281 Jun 2016