Drugs / OPT101
last change May 2026 re-read 3 minutes ago

OPT101

Peptide targets CD40

Developed for
type 1 diabetes mellitus · infectious disease with sepsis · pneumonia
Investigated by
Op-T LLC

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT06669403 Dec 2025 → Apr 2026 overdue infectious disease with sepsis, pneumonia Op-T LLC Not yet recruiting No outcome recorded
Phase 1 NCT05428943 Sep 2022 → Feb 2024 type 1 diabetes mellitus Op-T LLC Completed No outcome recorded
Phase 1 NCT04589403 Feb → Sep 2021 — Op-T LLC Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06964087 Apr → May 2026 overdue type 1 diabetes mellitus Op-T LLC Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as OPT101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04589403 ↗
3

NCT06964087 ↗

NCT06669403 ↗

NCT05428943 ↗

Modality Peptide “15-mer peptide with sequence based on the mouse CD154 domain interacting with CD40” NCT04589403 ↗
Route Intravenous “administered by a slow IV infusion” NCT04589403 ↗
Target CD40 “15-mer peptide with sequence based on the mouse CD154 domain interacting with CD40” NCT04589403 ↗