Drugs / Gestrinone
last change Oct 2025 re-read 2 minutes ago

Gestrinone

also known as A 46 745 · Dimetriose · Gestrinona · R 2323 · RU 2323

Small molecule

Developed for
endometriosis
Investigated by
Bio Meds Pharmaceutica Ltda · Biós Farmacêutica · Science Valley Research Institute

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT05570786 Feb 2023 → May 2025 endometriosis Science Valley Research Institute Completed No outcome recorded
Phase 41 trial
Phase 4 NCT06543550 Jul 2024 → Sep 2025 overdue endometriosis Bio Meds Pharmaceutica Ltda Recruiting No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Gestrinone ClinicalTrials.gov intervention name — accepted as the source's own label NCT05570786
1

NCT06543550

Known as A 46 745 ChEMBL registry synonym — accepted as the source's own label CHEMBL1868702
Known as Dimetriose ChEMBL registry synonym — accepted as the source's own label CHEMBL1868702
Known as Gestrinona ChEMBL registry synonym — accepted as the source's own label CHEMBL1868702
Known as R 2323 ChEMBL registry synonym — accepted as the source's own label CHEMBL1868702
Known as RU 2323 ChEMBL registry synonym — accepted as the source's own label CHEMBL1868702
Action Inhibit “Gestrinone is a synthetic derivative of 19-nortestosterone with anti-estrogen, anti-progestin, androgenic, and weak estrogen-like action.” NCT05570786
Modality Small molecule “Gestrinone is a synthetic derivative of 19-nortestosterone with anti-estrogen, anti-progestin, androgenic, and weak estrogen-like action.” NCT05570786
Route Other “subdermal implantation of the gestrinone (85 mg)” NCT05570786