Drugs / Lumiracoxib
Trials 16 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT01481610 | Jan → Nov 2012 | arthropathy, chronic renal failure syndrome | Hospital Central Sur de Pemex | Terminated | No outcome recorded |
| Phase 38 trials | ||||||
| Phase 3 | NCT00170872 | Nov 2004 → Jul 2005 | osteoarthritis, rheumatoid arthritis | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00154219 | Nov 2004 → Oct 2006 | osteoarthritis, hip | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00145301 | Sep 2004 → Nov 2005 | osteoarthritis | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00475800 | Jan → Dec 2004 | osteoarthritis, knee | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00476034 | Dec 2003 → Nov 2004 | osteoarthritis | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00367315 | Sep 2003 → Feb 2004 | osteoarthritis, knee | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00366938 | Sep 2003 → Mar 2004 | osteoarthritis, knee | Novartis | Completed | No outcome recorded |
| Phase 3 | NCT00267215 | Nov 2000 → Feb 2001 | osteoarthritis | Novartis | Completed | No outcome recorded |
| Phase 47 trials | ||||||
| Phase 4 | NCT00419796 | Nov 2006 → Sep 2007 | osteoarthritis | Novartis | Completed | No outcome recorded |
| Phase 4 | NCT00333567 | Aug 2006 → ? | — | Novartis | Completed | No outcome recorded |
| Phase 4 | NCT00350155 | May 2006 → ? | — | Novartis | Completed | No outcome recorded |
| Phase 4 | NCT00348491 | Feb → May 2006 | — | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 4 | NCT00267176 | Nov 2005 → Sep 2006 | hypertensive disorder, osteoarthritis | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 4 | NCT00170781 | Jun 2005 → ? | gout | Novartis | Completed | No outcome recorded |
| Phase 4 | NCT00170898 | Nov 2004 → ? | musculoskeletal system disorder | Novartis | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 20 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Lumiracoxib | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00170898 ↗ |
| Known as | COX189 | “A 13-week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo-controlled, Parallel Group Trial of Lumiracoxib (COX189) 100 mg o.d. in Patients With Primary Hip...” NCT00154219 ↗ |
| Known as | Prexige | “We compared the analgesic efficacy of the novel cyclo-oxygenase-2 selective inhibitor lumiracoxib (Prexige) versus placebo and celecoxib in patients with knee osteoarthritis.” PMID 16469112 ↗ Jan 2006 |
| Action | Inhibit | “lumiracoxib, a novel selective cyclooxygenase-2 (COX-2) inhibitor” PMID 18328090 ↗ Mar 2008 |
| Modality | Small molecule | — CHEMBL404108 ↗ |
| Route | Oral | “lumiracoxib 100 mg once daily (o.d.) (n = 427), celecoxib 200 mg o.d. (n = 419), or matching placebo o.d. (n = 416) administered orally.” PMID 21607551 ↗ May 2011 |
| Target | PTGS2 | “cyclo-oxygenase-2 selective inhibitor lumiracoxib” PMID 16469112 ↗ Jan 2006 |