Drugs / RO5458640
last change Mar 2013 re-read 3 minutes ago

RO5458640

also known as RG-7212

targets TNFSF12 via inhibition

Developed for
neoplasm
Investigated by
Hoffmann-La Roche

Trials 1

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01383733 Jul 2011 → Mar 2013 neoplasm Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RO5458640 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01383733 ↗
Known as RG-7212 ChEMBL registry synonym — accepted as the source's own label CHEMBL2109600 ↗
Action Inhibit “Tumor necrosis factor ligand superfamily member 12 inhibitor” CHEMBL2109600 ↗
Route Intravenous “receive ascending doses of RO5458640 intravenously” NCT01383733 ↗
Target TNFSF12 “Tumor necrosis factor ligand superfamily member 12 inhibitor” CHEMBL2109600 ↗