Drugs / NXP900
last change Dec 2025 re-read 2 minutes ago

NXP900

also known as DERIVATIVE 11A · ECF506

Small molecule targets SRC, YES1 via inhibition

Developed for
kidney cancer · lung adenocarcinoma · lung cancer · mesothelioma · non-small cell squamous lung carcinoma
Investigated by
Nuvectis Pharma, Inc.

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07315113 Dec 2025 → Dec 2026 expected lung cancer Nuvectis Pharma, Inc. Recruiting No outcome recorded
Phase 1 NCT05873686 Oct 2023 → Mar 2027 expected kidney cancer, lung adenocarcinoma, mesothelioma, non-small cell squamous lung carcinoma Nuvectis Pharma, Inc. Recruiting No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as NXP900 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07315113
1

NCT05873686

Known as DERIVATIVE 11A ChEMBL registry synonym — accepted as the source's own label CHEMBL3824089
Known as ECF506 ChEMBL registry synonym — accepted as the source's own label CHEMBL3824089
Action Inhibit “NXP900 is an orally administered SRC/YES1 kinase inhibitor” NCT05873686
Modality Small molecule CHEMBL3824089
Route Oral “NXP900 is an orally administered SRC/YES1 kinase inhibitor” NCT05873686
Target SRC “NXP900 is an orally administered SRC/YES1 kinase inhibitor” NCT05873686
Target YES1 “NXP900 is an orally administered SRC/YES1 kinase inhibitor” NCT05873686