Drugs / Bakuchiol
last change Dec 2025 re-read 2 minutes ago

Bakuchiol

also known as (s)-bakuchiol · Sytenol a · UP 256

Small molecule

Developed for
hyperpigmentation of the skin · skin atrophy
Investigated by
Hasanuddin University · Henry Ford Health System · University of California, Davis

Trials 3 · a red edge is where a trial was stopped

20162017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT03112863 Mar 2017 → Mar 2019 University of California, Davis Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07477288 Mar → Sep 2025 skin atrophy Hasanuddin University Completed No outcome recorded
Phase not applicable1 trial
NCT06833996 Feb 2016 → May 2018 hyperpigmentation of the skin Henry Ford Health System Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Bakuchiol ClinicalTrials.gov intervention name — accepted as the source's own label NCT03112863
2

NCT07477288

NCT06833996

Known as (s)-bakuchiol ChEMBL registry synonym — accepted as the source's own label CHEMBL262344
Known as Sytenol a ChEMBL registry synonym — accepted as the source's own label CHEMBL262344
Known as UP 256 ChEMBL registry synonym — accepted as the source's own label CHEMBL262344
Action Inhibit “bakuchiol had inhibitory effects on melanin synthesis” NCT06833996
Modality Small molecule “Bakuchiol is a meroterpene phenol derived from plant sources” NCT06833996
Route Topical “Bakuchiol 0.5% applied to face twice daily” NCT03112863