Drugs / KB001
last change Sep 2013 re-read 3 minutes ago

KB001

also known as Humaneered

Monoclonal antibody

Developed for
cystic fibrosis · Pseudomonas aeruginosa infectious disease
Investigated by
Humanigen, Inc.

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT00691587 Apr 2008 → Mar 2009 Pseudomonas aeruginosa infectious disease Humanigen, Inc. Completed No outcome recorded
Phase 1/2 NCT00638365 Mar 2008 → Mar 2009 cystic fibrosis Humanigen, Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as KB001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00638365 ↗
1

NCT00691587 ↗

Known as Humaneered ChEMBL registry synonym — accepted as the source's own label CHEMBL2109536 ↗
Action Inhibit “KB001 is a PEGylated, recombinant, anti-Pseudomonas-PcrV antibody Fab' fragment that blocks the function of Pa TTSS.” PMID 24019259 ↗ Sep 2013
Modality Monoclonal antibody “KB001, a monoclonal antibody” NCT00638365 ↗
Route Intravenous “Single-dose, 3mg/kg or 10mg/kg dose administered intravenously” NCT00638365 ↗