Drugs / valdecoxib

Regulatory milestones approvals, filings & regulatory actions · 4 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Withdrawn EU (EMA) Bextra 2008-03-27 europa.eu
Label expansion US (FDA) BEXTRA 2004-04-23 fda.gov
Approved EU (EMA) Bextra 2003-03-27 europa.eu
Approved US (FDA) BEXTRA 2001-11-16 fda.gov

Trials 8 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00115752 Jun 2005 → Oct 2006 National Institute of Nursing Research (NINR) Completed No outcome recorded
Phase 33 trials
Phase 3 NCT00651300 Apr 2003 → Mar 2004 Pfizer Terminated No outcome recorded
Phase 3 NCT00092339 Aug → Sep 2002 Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 3 NCT00092300 May → Sep 2002 Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 43 trials
Phase 4 NCT00260325 Aug 2004 → Apr 2006 Penn State University Completed No outcome recorded
Phase 4 NCT00660855 Jun → Jul 2004 Pfizer Terminated No outcome recorded
Phase 4 NCT00122096 Nov 2002 → Jan 2006 University of Washington Completed No outcome recorded
Phase not applicable1 trial
NCT00021996 Jan 2001 → Feb 2004 cancer of unknown primary site Dana-Farber Cancer Institute Completed No outcome recorded
Also used as a comparator or background therapy in 20 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT00602901 Background Jul 2004 → Oct 2006 chronic pain syndrome, subacute bursitis Palmer College of Chiropractic Completed No outcome recorded
Phase 2 NCT00650624 Comparator Jun 2003 → Jan 2004 osteoarthritis, knee Pfizer Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00419549 Comparator Oct 2003 → Sep 2005 acute pancreatitis All India Institute of Medical Sciences Terminated No outcome recorded
Phase 38 trials
Phase 3 NCT00652808 Comparator May → Sep 2004 osteoarthritis, knee Pfizer Completed No outcome recorded
Phase 3 NCT00650039 Comparator Mar 2004 → Feb 2005 Pfizer Completed No outcome recorded
Phase 3 NCT00648258 Comparator Jul 2003 → Apr 2004 osteoarthritis Pfizer Completed No outcome recorded
Phase 3 NCT00647829 Comparator Feb → Dec 2003 pharyngitis Pfizer Completed No outcome recorded
Phase 3 NCT00636064 Comparator Jan 2003 → Jan 2004 Pfizer Completed No outcome recorded
Phase 47 trials
Phase 4 NCT00650598 Comparator Mar → Aug 2004 neuropathy, painful Pfizer Completed No outcome recorded
Phase 4 NCT01361789 Comparator Jan 2004 → Dec 2009 Asker & Baerum Hospital Completed No outcome recorded
Phase 4 NCT00657449 Comparator Jun 2003 → Oct 2004 Pfizer Terminated No outcome recorded
Phase 4 NCT00650455 Comparator Feb 2003 → Jan 2005 rheumatoid arthritis Pfizer Completed No outcome recorded
Phase 4 NCT00649415 Comparator Jan → Jul 2003 primary dysmenorrhea Pfizer Completed No outcome recorded
Phase not applicable2 trials
NCT01541137 Comparator Mar 2004 → Sep 2008 Helsinki University Central Hospital Completed No outcome recorded
NCT00763997 Comparator Feb → Dec 2004 platelet aggregation, spontaneous Ruhr University of Bochum Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 29 sources stand behind the page.

FieldValueCited text
Known as Valdecoxib ClinicalTrials.gov intervention name — accepted as the source's own label NCT00419549
26

NCT00660855

NCT00653354

NCT00636064

NCT00650039

NCT00649415

NCT00661635

NCT00657449

NCT00650455

NCT00260325

NCT00683137

NCT00092339

NCT00122096

NCT00651300

NCT00649610

NCT00021996

NCT01541137

NCT00671320

NCT00648258

NCT00650624

NCT00647829

NCT00652808

NCT00650598

NCT00763997

NCT01361789

NCT00092300

NCT00115752

Known as Bextra “40 mg parecoxib (Dynastat, Pfizer®) one hour before surgery and 40 mg valdecoxib (prodrug of parecoxib, Bextra, Pfizer®)were given 8 hour after surgery.” NCT01361789
2

Bextra® (Valdecoxib) 20 Mg Twice Daily, Bextra® 40 Mg Once Daily, And Placebo” NCT00647829

Bextra: po, 10mg, qd, six weeks” NCT00602901

Known as NSC-759846 ChEMBL registry synonym — accepted as the source's own label CHEMBL865
Known as SC-65872 “Clinical Protocol for a Randomized Double-Blind, Placebo-Controlled Comparison of the Analgesic Activity of Valdecoxib (SC-65872) 40mg BID as Add-On Therapy to Opioid...” NCT00021996
Known as Valdyn ChEMBL registry synonym — accepted as the source's own label CHEMBL865
Known as Valdyn (previously kudeq) ChEMBL registry synonym — accepted as the source's own label CHEMBL865
Action Inhibit “COX inhibitor” NCT00115752
Modality Small molecule CHEMBL865
Route Oral “Patients receive oral valdecoxib twice daily” NCT00021996
Target PTGS2 “selective COX-2 inhibitor” NCT00419549