Drugs / AZD1236
last change Aug 2010 re-read 3 minutes ago

AZD1236

Small molecule targets MMP12, MMP9 via inhibition

Developed for
chronic obstructive pulmonary disease · cystic fibrosis
Investigated by
AstraZeneca

Trials 5

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT01007929 Oct → Nov 2009 — AstraZeneca Terminated No outcome recorded
Phase 1 NCT00767052 Sep → Dec 2008 — AstraZeneca Completed No outcome recorded
Phase 23 trials
Phase 2 NCT00812045 Dec 2009 → Aug 2010 cystic fibrosis AstraZeneca Withdrawn No outcome recorded
Phase 2 NCT00758459 Sep 2008 → Mar 2009 chronic obstructive pulmonary disease AstraZeneca Completed No outcome recorded
Phase 2 NCT00758706 Sep 2008 → May 2009 chronic obstructive pulmonary disease AstraZeneca Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as AZD1236 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00758459 ↗
4

NCT00767052 ↗

NCT01007929 ↗

NCT00812045 ↗

NCT00758706 ↗

Action Inhibit “Matrix metalloproteinase 12 inhibitor” CHEMBL4297352 ↗
1

“Matrix metalloproteinase 9 inhibitor” CHEMBL4297352 ↗

Modality Small molecule — CHEMBL4297352 ↗
Route Oral “oral tablet” NCT00758459 ↗
Target MMP12 “Matrix metalloproteinase 12 inhibitor” CHEMBL4297352 ↗
Target MMP9 “Matrix metalloproteinase 9 inhibitor” CHEMBL4297352 ↗