Drugs / iratumumab
last change Nov 2009 re-read 3 minutes ago

iratumumab

also known as MDX-060

Monoclonal antibody targets TNFRSF8

Developed for
lymphoma · Hodgkins lymphoma
Investigated by
Bristol-Myers Squibb · Memorial Sloan Kettering Cancer Center · National Cancer Institute (NCI)

Trials 3

2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00059995 Jan 2003 → Oct 2007 lymphoma Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00298467 Feb 2006 → ? lymphoma Bristol-Myers Squibb Withdrawn No outcome recorded Stop: Business
Phase 2 NCT00284804 Nov 2005 → May 2008 Hodgkins lymphoma Bristol-Myers Squibb Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as iratumumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT00059995 ↗
Known as MDX-060 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00298467 ↗
1

NCT00284804 ↗

Action Inhibit “inhibits growth of CD30-expressing tumor cells” PMID 17515574 ↗ May 2007
Modality Monoclonal antibody “human anti-CD30 immunoglobulin (Ig) G1kappa monoclonal antibody” PMID 17515574 ↗ May 2007
Route Intravenous “administered intravenously” PMID 17515574 ↗ May 2007
Target TNFRSF8 “Tumor necrosis factor receptor superfamily member 8 other” CHEMBL2108612 ↗