Drugs / RG002C0106
last change Aug 2026 re-read 3 minutes ago

RG002C0106

Small interfering RNA (siRNA) targets C3 via inhibition

Developed for
IgA glomerulonephritis
Investigated by
Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07445906 Mar → Dec 2026 expected IgA glomerulonephritis, impaired renal function disease Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06494527 Oct 2024 → Aug 2026 overdue — Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd. Active not recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07305974 Sep 2025 → Mar 2029 expected IgA glomerulonephritis Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as RG002C0106 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07305974 ↗
2

NCT07445906 ↗

NCT06494527 ↗

Action Inhibit “inhibit the expression of C3 protein” NCT06494527 ↗
Modality Small interfering RNA (siRNA) “is a siRNA drug” NCT06494527 ↗
Route Subcutaneous “receive subcutaneous injection for administration” NCT06494527 ↗
Target C3 “targeting complement C3” NCT06494527 ↗