Drugs / Tetrodotoxin
Tetrodotoxin
also known as
TTX · Araregai toxin · Babylonia japonica toxin 1 · Bjt 1 · Maculotoxin · Pft-1 toxin · Spheroidine · Tarichatoxin · +4 more
Trials 4
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT04083833 | Feb → Mar 2018 | short QT syndrome 7 | Wex Pharmaceuticals Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01527734 | Dec 2011 → Jan 2012 | — | Wex Pharmaceuticals Inc. | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT01655823 | Jul 2012 → Jan 2015 | neuropathy, painful, peripheral neuropathy | Wex Pharmaceuticals Inc. | Terminated | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00726011 | Jul 2008 → Dec 2011 | cancer | Wex Pharmaceuticals Inc. | Completed | No outcome recorded |
| Comparator or background therapy2 trials | ||||||
| Phase 2 | NCT05359133 Comparator | Apr 2022 → Oct 2024 | chemotherapy-induced neuropathy | Wex Pharmaceuticals Inc. | Terminated | No outcome recorded Stop: Business |
| Phase 3 | NCT00725114 Comparator | Apr 2008 → Nov 2012 | cancer | Wex Pharmaceuticals Inc. | Completed | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tetrodotoxin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01527734 ↗ |
| Known as | Araregai toxin | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Babylonia japonica toxin 1 | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Bjt 1 | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Maculotoxin | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Pft-1 toxin | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Spheroidine | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Tarichatoxin | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Tectin | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Tetrodotoxina | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Tetrodotoxine | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | Tettrodotoxin | ChEMBL registry synonym — accepted as the source's own label CHEMBL507974 ↗ |
| Known as | TTX | “The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From Chemotherapy Treatment” NCT01655823 ↗2“Comparison Study of Liquid and Lyophilized Formulations of Subcutaneous Tetrodotoxin (TTX) in Healthy Volunteers” NCT01527734 ↗ “The test product was 30 µg/mL tetrodotoxin (TTX) for injection, Lot No. F141124-001.” NCT04083833 ↗ |
| Action | Inhibit | “Tetrodotoxin (TTX) is a selective blocker of Na+ channels” NCT00725114 ↗ |
| Modality | Small molecule | — CHEMBL507974 ↗ |
| Route | Subcutaneous | “Subcutaneous tetrodotoxin (30 µg b.i.d.) or placebo will be administered” NCT00725114 ↗ |