Drugs / Tomuzotuximab
last change Sep 2020 re-read 2 minutes ago

Tomuzotuximab

also known as CetuGEX

Monoclonal antibody targets EGFR via inhibition

Developed for
cancer · head and neck squamous cell carcinoma
Investigated by
Glycotope GmbH

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03360734 Nov 2017 → May 2020 cancer Glycotope GmbH Completed No outcome recorded
Phase 1 NCT01222637 Aug 2010 → Aug 2012 cancer Glycotope GmbH Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02052960 Feb 2014 → Aug 2017 head and neck squamous cell carcinoma Glycotope GmbH Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Tomuzotuximab ClinicalTrials.gov intervention name — accepted as the source's own label NCT03360734
Known as CetuGEX “Tomuzotuximab (CetuGEX®) is an improved second-generation anti-epidermal growth factor receptor (EGFR) antibody” NCT03360734
2

NCT02052960

NCT01222637

Action Inhibit “receptor blockade by the antibody” PMID 29464112 Feb 2018
Modality Monoclonal antibody “Two monoclonal antibodies, Gatipotuzumab is anti-TAMUC1, Tomuzotuximab is anti-EGFR” NCT03360734
1

CHEMBL4297842

Route Intravenous “after intravenous administration” NCT01222637
Target EGFR “Tomuzotuximab (CetuGEX®) is an improved second-generation anti-epidermal growth factor receptor (EGFR) antibody” NCT03360734