Drugs / ENCENICLINE

Trials 14 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT01984736 Jun 2013 → Dec 2014 FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 1 NCT01984723 Jun 2013 → Feb 2014 impaired renal function disease FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 1 NCT00766363 Oct 2008 → Mar 2009 Alzheimer disease FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 1 NCT01556763 Apr → Aug 2008 schizoaffective disorder, schizophrenia FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 23 trials
Phase 2 NCT02246075 Jul 2015 → Oct 2016 Alzheimer disease FORUM Pharmaceuticals Inc Withdrawn No outcome recorded
Phase 2 NCT01764243 Nov 2012 → Jun 2015 Alzheimer disease Tanabe Pharma Corporation Completed No outcome recorded
Phase 2 NCT01480232 Dec 2011 → Sep 2015 nicotine dependence A. Eden Evins Terminated No outcome recorded
Phase 37 trials
Phase 3 NCT02327182 Dec 2014 → Sep 2015 Alzheimer disease Tanabe Pharma Corporation Terminated No outcome recorded
Phase 3 NCT02004392 Jun 2014 → Aug 2017 Alzheimer disease FORUM Pharmaceuticals Inc Terminated No outcome recorded
Phase 3 NCT01969136 Oct 2013 → Jan 2017 Alzheimer disease FORUM Pharmaceuticals Inc Terminated No outcome recorded
Phase 3 NCT01969123 Oct 2013 → Jan 2017 Alzheimer disease FORUM Pharmaceuticals Inc Terminated No outcome recorded
Phase 3 NCT01714713 Jun 2013 → Oct 2015 schizophrenia FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 3 NCT01714661 Oct 2012 → Dec 2015 schizophrenia FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 3 NCT01716975 Oct 2012 → Feb 2016 schizophrenia FORUM Pharmaceuticals Inc Completed No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01487135 Comparator Dec 2011 → Sep 2013 FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01073228 Comparator Apr 2010 → Nov 2011 Alzheimer disease FORUM Pharmaceuticals Inc Completed No outcome recorded
Phase 2 NCT00968851 Comparator Dec 2009 → Jan 2011 schizophrenia FORUM Pharmaceuticals Inc Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 18 sources stand behind the page.

FieldValueCited text
Known as ENCENICLINE ChEMBL registry synonym — accepted as the source's own label CHEMBL2151572
Known as Enceniclina ChEMBL registry synonym — accepted as the source's own label CHEMBL2151572
Known as ENCENICLINE HYDROCHLORIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL2151572
Known as EVP-6124 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01714661
14

NCT01984723

NCT00766363

NCT02246075

NCT00968851

NCT01716975

NCT01480232

NCT01073228

NCT01556763

NCT01487135

NCT02004392

NCT01969136

NCT01969123

NCT01714713

NCT01984736

Known as EVP-6124 HYDROCHLORIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL2151572
Known as MT-4666 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02327182
1

NCT01764243

Action Activate “Neuronal acetylcholine receptor protein alpha-7 subunit partial agonist” CHEMBL2151572
1

“Alpha-7 Nicotinic Acetylcholine Receptor Agonist” NCT00766363

Modality Small molecule CHEMBL2151572
Route Oral “Study drug will be supplied as capsules and will be orally administered once daily” NCT00766363
Target CHRNA7 “Neuronal acetylcholine receptor protein alpha-7 subunit partial agonist” CHEMBL2151572