Drugs / SRA737
last change Apr 2020 re-read 3 minutes ago

SRA737

also known as CCT-245737 · CCT245737 FREE BASE · PNT-737

Small molecule targets CHEK1 via inhibition

Developed for
cancer · non-Hodgkin lymphoma
Investigated by
Sierra Oncology LLC - a GSK company

Trials 2

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT02797964 Jul 2016 → Oct 2019 non-Hodgkin lymphoma Sierra Oncology LLC - a GSK company Completed No outcome recorded
Phase 1/2 NCT02797977 Jul 2016 → Apr 2020 cancer Sierra Oncology LLC - a GSK company Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as SRA737 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02797964 ↗
1

NCT02797977 ↗

Known as CCT-245737 ChEMBL registry synonym — accepted as the source's own label CHEMBL4169078 ↗
Known as CCT245737 FREE BASE ChEMBL registry synonym — accepted as the source's own label CHEMBL4169078 ↗
Known as PNT-737 ChEMBL registry synonym — accepted as the source's own label CHEMBL4169078 ↗
Action Inhibit “SRA737 is a potent, highly selective, orally bioavailable small molecule inhibitor of Chk1” NCT02797964 ↗
Modality Small molecule “SRA737 is a potent, highly selective, orally bioavailable small molecule inhibitor of Chk1” NCT02797964 ↗
Route Oral “SRA737 will be administered orally on each day of a 28-day cycle” NCT02797964 ↗
Target CHEK1 “SRA737 is a potent, highly selective, orally bioavailable small molecule inhibitor of Chk1” NCT02797964 ↗