Drugs / Lunacalcipol
last change Jul 2013 re-read 3 minutes ago

Lunacalcipol

also known as CTA018

Small molecule targets VDR via activation

Developed for
secondary hyperparathyroidism of renal origin · chronic renal failure syndrome · end stage renal failure · psoriasis
Investigated by
OPKO Health, Inc. · OPKO IP Holdings II, Inc.

Trials 3

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01453634 Jan → Jul 2013 end stage renal failure, secondary hyperparathyroidism of renal origin OPKO Health, Inc. Withdrawn No outcome recorded
Phase 2 NCT00742716 Oct 2008 → Feb 2010 chronic renal failure syndrome, secondary hyperparathyroidism of renal origin OPKO IP Holdings II, Inc. Completed No outcome recorded
Phase 2 NCT00384098 Sep 2006 → May 2007 psoriasis OPKO Health, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Lunacalcipol ClinicalTrials.gov intervention name — accepted as the source's own label NCT01453634 ↗
Known as CTA018 “A Randomized, Open Label, Four Week, Pharmacodynamic/Pharmacokinetic, Efficacy, and Safety Study of Lunacalcipol (CTA018) Injection in Subjects With Stage 5 Chronic Kidney...” NCT01453634 ↗
2

NCT00742716 ↗

NCT00384098 ↗

Action Activate “Vitamin D receptor agonist” CHEMBL2105705 ↗
Modality Small molecule — CHEMBL2105705 ↗
Route Topical “Topically Applied CTA018” NCT00384098 ↗
Target VDR “Vitamin D receptor agonist” CHEMBL2105705 ↗