Drugs / INDUSATUMAB VEDOTIN
last change May 2017 re-read 3 minutes ago

INDUSATUMAB VEDOTIN

targets GUCY2C

Developed for
gastric adenocarcinoma · gastroesophageal junction adenocarcinoma · digestive system cancer · pancreatic adenocarcinoma
Investigated by
Millennium Pharmaceuticals, Inc.

Trials 4

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02391038 Dec 2014 → Oct 2015 gastric adenocarcinoma, gastroesophageal junction adenocarcinoma Millennium Pharmaceuticals, Inc. Terminated No outcome recorded
Phase 1 NCT01577758 Jun 2012 → Feb 2014 digestive system cancer Millennium Pharmaceuticals, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02202759 Aug 2014 → Jan 2016 gastric adenocarcinoma, gastroesophageal junction adenocarcinoma Millennium Pharmaceuticals, Inc. Terminated No outcome recorded Stop: Business
Phase 2 NCT02202785 Jul 2014 → Jan 2016 pancreatic adenocarcinoma Millennium Pharmaceuticals, Inc. Terminated No outcome recorded Stop: Business

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as INDUSATUMAB VEDOTIN ChEMBL registry synonym — accepted as the source's own label CHEMBL4298045 ↗
Known as Indusatumab vedotina ChEMBL registry synonym — accepted as the source's own label CHEMBL4298045 ↗
Known as Indusatumab vedotine ChEMBL registry synonym — accepted as the source's own label CHEMBL4298045 ↗
Known as MLN0264 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02202759 ↗
3

NCT01577758 ↗

NCT02391038 ↗

NCT02202785 ↗

Known as TAK-264 “A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.” PMID 28527133 ↗ May 2017
Route Intravenous “intravenous (IV) infusion” NCT02202759 ↗
Target GUCY2C “Heat-stable enterotoxin receptor binding agent” CHEMBL4298045 ↗