Drugs / AZINTUXIZUMAB VEDOTIN
last change Apr 2021 re-read 2 minutes ago

AZINTUXIZUMAB VEDOTIN

targets SLAMF7

Developed for
plasma cell myeloma
Investigated by
AbbVie

Trials 2 · a red edge is where a trial was stopped

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02951117 Aug 2017 → Jul 2020 plasma cell myeloma AbbVie Withdrawn No outcome recorded
Phase 1 NCT02462525 May 2015 → Dec 2017 plasma cell myeloma AbbVie Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as AZINTUXIZUMAB VEDOTIN ChEMBL registry synonym — accepted as the source's own label CHEMBL4297859
Known as ABBV-838 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02951117
1

NCT02462525

Known as Azintuxizumab vedotina ChEMBL registry synonym — accepted as the source's own label CHEMBL4297859
Known as Azintuxizumab vedotine ChEMBL registry synonym — accepted as the source's own label CHEMBL4297859
Route Intravenous “Eligible patients (≥18 years) received ABBV-838 (3+3 design) intravenously starting from 0.6 mg/kg up to 6.0 mg/kg for 3-week dosing intervals (Q3W).” PMID 31969330 Jan 2020
Target SLAMF7 “First-in-Human Phase I Study of ABBV-838, an Antibody-Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma.” PMID 31969330 Jan 2020