Drugs / MOC31PE
last change Dec 2016 re-read 3 minutes ago

MOC31PE

Other / unclassified targets EPCAM

Developed for
carcinoma · colorectal neoplasm
Investigated by
Oslo University Hospital

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01061645 Sep 2010 → Feb 2012 carcinoma Oslo University Hospital Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02219893 Aug 2014 → Dec 2016 colorectal neoplasm Oslo University Hospital Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MOC31PE ClinicalTrials.gov intervention name — accepted as the source's own label NCT02219893 ↗
1

NCT01061645 ↗

Action Inhibit “The effector moieties of the IT used here, the Pseudomonas exotoxin A (PE), inhibits protein synthesis in eukaryotic cells by catalytic inactivation (ribosylation) of...” NCT01061645 ↗
Modality Other / unclassified “MOC31PE is an immunotoxin” NCT02219893 ↗
Target EPCAM “Epithelial cell adhesion molecule binding agent” CHEMBL2109265 ↗