Drugs / Relacorilant

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) LIFYORLI (COPACKAGED) 2026-03-25 fda.gov

Trials 25 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 114 trials
Phase 1 NCT05347979 May → Jul 2022 Cushing syndrome, neoplasm Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT04795479 Jan → May 2021 Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT04373265 Sep 2020 → Oct 2023 adrenal cortex carcinoma Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT06094738 Sep → Nov 2020 Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT06094725 Jan → Dec 2020 liver disease, severe congenital Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT03674814 Oct 2018 → Jun 2024 prostate cancer University of Chicago Completed No outcome recorded
Phase 1 NCT03540836 May → Jul 2018 Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT03512548 Apr 2018 → Jul 2019 Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT03457597 Mar → Apr 2018 Corcept Therapeutics Completed No outcome recorded
Phase 1 NCT03442621 Jan → Feb 2018 Corcept Therapeutics Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02762981 May 2016 → May 2020 cancer Corcept Therapeutics Completed No outcome recorded
Phase 26 trials
Phase 2 NCT07259317 Jan 2026 → Sep 2027 expected pancreatic ductal adenocarcinoma Corcept Therapeutics Recruiting No outcome recorded
Phase 2 NCT06906341 Apr 2025 → Aug 2026 overdue endometrial cancer, fallopian tube cancer, ovarian cancer, peritoneal neoplasm Corcept Therapeutics Recruiting No outcome recorded
Phase 2 NCT05726292 Jan 2025 → Oct 2027 expected prostate adenocarcinoma University of Chicago Recruiting No outcome recorded
Phase 2 NCT03776812 Apr 2019 → Mar 2021 fallopian tube carcinoma, ovarian cancer, primary peritoneal carcinoma Corcept Therapeutics Completed No outcome recorded
Phase 2 NCT03604198 May 2018 → Dec 2026 expected endogenous Cushing syndrome Corcept Therapeutics Active not recruiting No outcome recorded
Phase 2 NCT02804750 Jun 2016 → Sep 2018 endogenous Cushing syndrome Corcept Therapeutics Completed No outcome recorded
Phase 34 trials
Phase 3 NCT05257408 Jun 2022 → Mar 2025 overdue fallopian tube neoplasm, ovarian neoplasm, peritoneal neoplasm Corcept Therapeutics Active not recruiting No outcome recorded
Phase 3 NCT04308590 Jul 2020 → Sep 2024 Cushing syndrome Corcept Therapeutics Completed No outcome recorded
Phase 3 NCT04329949 Jun 2020 → Aug 2021 pancreatic ductal adenocarcinoma Corcept Therapeutics Terminated No outcome recorded
Phase 3 NCT03697109 Nov 2018 → Apr 2024 Cushing syndrome Corcept Therapeutics Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 26 sources stand behind the page.

FieldValueCited text
Known as Relacorilant ClinicalTrials.gov intervention name — accepted as the source's own label NCT03697109
19

NCT06094725

NCT05257408

NCT04373265

NCT06094738

NCT03512548

NCT04329949

NCT04795479

NCT03674814

NCT02762981

NCT03442621

NCT03604198

NCT03457597

NCT04308590

NCT05726292

NCT03540836

NCT05347979

NCT06906341

NCT07259317

NCT03776812

Known as CORT125134 “relacorilant (CORT125134)” NCT03604198
5

NCT06094790

NCT03067376

NCT06094712

NCT02804750

NCT03508635

Action Inhibit “a novel glucocorticoid receptor (GR) antagonist” NCT02762981
1

“Glucocorticoid receptor antagonist” CHEMBL4068611

Modality Small molecule “Relacorilant is a small molecule antagonist of the glucocorticoid receptor (GR).” NCT03776812
Route Oral oral relacorilant lead-in once-daily” NCT02762981
Target NR3C1 “Glucocorticoid receptor antagonist” CHEMBL4068611