Drugs / ALN-KHK
last change Apr 2025 re-read 3 minutes ago

ALN-KHK

Developed for
type 2 diabetes mellitus
Investigated by
Alnylam Pharmaceuticals

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05761301 Mar 2023 → Apr 2025 type 2 diabetes mellitus Alnylam Pharmaceuticals Terminated No outcome recorded Stop: Business

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2023-12-13 Alnylam Pharmaceuticals Results Alnylam Highlights Significant Progress with Platform Innovation and Clinical Pipeline at R&D Day alnylam.com ↗
Positive Initial Phase 1 Results with ALN-KHK Demonstrate Robust Target Engagement and an Encouraging Safety Profile, Supporting Continued Development as a Novel Treatment for Type 2 Diabetes Mellitus
2022-12-21 Alnylam Pharmaceuticals Regulatory Alnylam Submits CTA Application for ALN-KHK, an Investigational RNAi Therapeutic for the Treatment of Type 2 Diabetes alnylam.com ↗

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as ALN-KHK ClinicalTrials.gov intervention name — accepted as the source's own label NCT05761301 ↗
Route Subcutaneous “ALN-KHK will be administered by subcutaneous (SC) injection.” NCT05761301 ↗