Drugs / CART-EGFR-IL13Ra2 Cells
last change Jul 2025 re-read 3 minutes ago

CART-EGFR-IL13Ra2 Cells

also known as CART-EGFR-IL13Rα2 cells

Cell therapy targets EGFR, IL13RA2

Developed for
glioblastoma
Investigated by
Kite Pharma (a Gilead Company) · University of Pennsylvania

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06973096 Jul 2025 → Jul 2042 expected glioblastoma University of Pennsylvania Recruiting No outcome recorded
Phase 1 NCT05168423 Feb 2023 → Dec 2039 expected glioblastoma University of Pennsylvania Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CART-EGFR-IL13Ra2 Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT05168423 ↗
1

NCT06973096 ↗

Known as CART-EGFR-IL13Rα2 cells “or CART-EGFR-IL13Rα2 cells, in patients with EGFR-amplified rGBM” PMID 40451950 ↗ Jun 2025
Modality Cell therapy “bivalent chimeric antigen receptor (CAR) T cells targeting epidermal growth factor receptor (EGFR) epitope 806 and interleukin-13 receptor alpha 2 (IL-13Rα2)” PMID 40451950 ↗ Jun 2025
Route Intrathecal “via intrathecal administration” NCT05168423 ↗
Target EGFR “targeting epidermal growth factor receptor (EGFR) epitope 806” PMID 40451950 ↗ Jun 2025