Drugs / Bone morphogenetic protein 7
last change May 2017 re-read 2 minutes ago

Bone morphogenetic protein 7

also known as BMP-7 · 38A BMP-7 · OP1
Developed for
avascular necrosis · osteoarthritis, knee
Investigated by
Stryker Biotech · University Hospital, Lille

Trials 2 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01133613 May 2010 → Oct 2011 osteoarthritis, knee Stryker Biotech Completed No outcome recorded
Phase not applicable1 trial
NCT02655120 Mar 2005 → May 2017 avascular necrosis University Hospital, Lille Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01111045 Comparator Apr 2010 → Aug 2011 osteoarthritis, knee Stryker Biotech Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Bone morphogenetic protein 7 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01133613
1

NCT01111045

Known as 38A BMP-7 “Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee” NCT01133613
Known as BMP-7 “Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee” NCT01111045
1

NCT02655120

Known as OP1 “The drilling is completed by a joint supply of autologous marrow unconcentrated and recombinant BMP7 ( OP1) .” NCT02655120
Modality Protein / enzyme biologic “recombinant BMP7” NCT02655120
Route Other “0.03 mg/ml BMP-7, single intraarticular knee injection” NCT01111045