Drugs / PABINAFUSP ALFA
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03128593 | Mar → Oct 2017 | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT03708965 | Jan 2019 → Dec 2026 expected | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Active not recruiting | No outcome recorded |
| Phase 2 | NCT03359213 | Jul 2018 → Oct 2019 | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Completed | No outcome recorded |
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT04348136 | Sep 2019 → Mar 2030 expected | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT03568175 | Aug 2018 → Feb 2020 | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT05594992 | Feb 2023 → Feb 2028 expected | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT04573023 | Feb 2022 → Oct 2027 expected | mucopolysaccharidosis type 2 | JCR Pharmaceuticals Co., Ltd. | Active not recruiting | No outcome recorded |
Evidence & citations 4 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | PABINAFUSP ALFA | ChEMBL registry synonym — accepted as the source's own label CHEMBL4594565 ↗ |
| Known as | JR-141 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05594992 ↗ |
| Modality | Protein / enzyme biologic | “A novel IDS fused with anti-human transferrin receptor antibody (JR-141) has been shown to penetrate the BBB” PMID 30595526 ↗ Dec 2018 |
| Route | Intravenous | “IV infusion (lyophilized powder), 0.01-2.0 mg/kg/week” NCT03128593 ↗ |