Drugs / Autologous tumor infiltrating lymphocytes (TILs)
last change May 2024 re-read 3 minutes ago

Autologous tumor infiltrating lymphocytes (TILs)

Cell therapy

Developed for
cervical carcinoma · malignant pleural mesothelioma · melanoma · non-small cell lung carcinoma
Investigated by
Suzhou BlueHorse Therapeutics Co., Ltd. · University Health Network, Toronto

Trials 2

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05366478 May 2022 → May 2024 overdue cervical carcinoma, melanoma, non-small cell lung carcinoma Suzhou BlueHorse Therapeutics Co., Ltd. Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02414945 May 2015 → Oct 2020 malignant pleural mesothelioma University Health Network, Toronto Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Autologous tumor infiltrating lymphocytes (TILs) ClinicalTrials.gov intervention name — accepted as the source's own label NCT05366478 ↗
1

NCT02414945 ↗

Action Deplete “TILs are a type of white blood cells that recognizes tumor cells and enter them which causes the tumor cells to break down.” NCT02414945 ↗
Modality Cell therapy “The investigational infusion product consists of autologous, in vitro-expanded tumor-infiltrating lymphocytes (TILs).” NCT02414945 ↗
Route Intravenous “The cells are given intravenously over a 20-30 minute infusion.” NCT02414945 ↗